Synonyms | Monoclonal EIF2B3 antibody, Anti-EIF2B3 antibody, Eukaryotic translation initiation factor 2B subunit 3 gamma antibody, EIF-2B antibody, EIF2Bgamma antibody, Translation initiation factor eIF-2B subunit gamma antibody, EIF2B3, EIFB3 2, EIFB3-2, EIFB3 2 antibody, EIFB3-2 antibody |
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Cross Reactivity | Human |
Applications | IHC, WB |
Immunogen | EIF2B3 antibody was raised in mouse using a full length recombinant protein of human EIF2B3 (NP_065098) produced in HEK293T cells, as the immunogen. |
Host | Mouse |
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Clone | 1D6 |
Isotype | IgG2b |
Method of Purification | EIF2B3 antibody was purified by affinity chromatography. |
Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 500 ug-1 mg/ml |
Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Recommendations | IHC: 1:150, WB: 1:2000 |
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Biological Significance | EIF2B3 is one of the subunits of initiation factor eIF2B, which catalyzes the exchange ofeukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis Cvirus internal ribosome entry site-mediated translation. Mutations in this gene have been associated withleukodystrophy with vanishing white matter. |
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Fitzgerald公司始于1989年,是全球著名的抗体、蛋白及其他科研试剂生产商。可提供超过45,000种产品,可为科研机构、诊断机构和制药公司提供包括单抗、多抗、天然和重组蛋白、ELISA试剂盒等多种试剂。
Fitzgerald的特色产品有PSA蛋白; CA 125, CA 15-3, CA 19-9 和 CA 50 抗体, GAPDH 抗体;Influenza单抗;心肌标志物如CKMM蛋白和Apo抗体;激素和类固醇多抗如**(testosterone)抗体, 孕酮(progesterone)抗体,和甲状腺素(thyroxine)抗体。