Synonyms | Monoclonal MRI1 antibody, Anti-MRI1 antibody, Methylthioribose-1-phosphate isomerase homolog antibody, MGC3207 antibody, MTNA antibody, Ypr118w antibody, Mediator of RhoA-dependent invasion antibody, MTR 1 P isomerase antibody, MRI1, MRI 1, MRI-1, MRI 1 antibody, MRI-1 antibody |
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Cross Reactivity | Human |
Applications | IF, IHC, WB |
Immunogen | MRI1 antibody was raised in mouse using a full length recombinant protein of human MRI1 (NP_115661) produced in HEK293T cells, as the immunogen. |
Host | Mouse |
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Clone | 6G9 |
Isotype | IgG1 |
Method of Purification | MRI1 antibody was purified by affinity chromatography. |
Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 500 ug-1 mg/ml |
Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Recommendations | IF: 1:100, IHC: 1:50, WB: 1:1000-2000 |
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Biological Significance | MRI1 catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate(MTRu-1-P). Independently from catalytic activity, it promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover |
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Fitzgerald公司始于1989年,是全球著名的抗体、蛋白及其他科研试剂生产商。可提供超过45,000种产品,可为科研机构、诊断机构和制药公司提供包括单抗、多抗、天然和重组蛋白、ELISA试剂盒等多种试剂。
Fitzgerald的特色产品有PSA蛋白; CA 125, CA 15-3, CA 19-9 和 CA 50 抗体, GAPDH 抗体;Influenza单抗;心肌标志物如CKMM蛋白和Apo抗体;激素和类固醇多抗如**(testosterone)抗体, 孕酮(progesterone)抗体,和甲状腺素(thyroxine)抗体。