Synonyms | Monoclonal SMC3 antibody, Anti-SMC3 antibody, Structural maintenance of chromosomes 3 antibody, SMC-3 antibody, SMC-3 antibody, SMC 3 antibody, SMC 3 antibody, SMC 3, SMC3, SMC-3 |
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Specificity | Mouse |
Applications | WB |
Immunogen | SMC3 antibody was raised in Rat using Mouse SMC3 and GST fusion protein as the immunogen. |
Host | Rat |
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Clone | KT75 |
Isotype | IgG2a |
Method of Purification | SMC3 antibody was purified by Protein G chromatography. |
Form & Buffer | Supplied in PBS containing 0.1% sodium azide as a preservative |
Concentration | 1 mg/ml |
Storage | Store at 4 deg C for up to 1 month. For long term storage, aliquot and store at -20 to -80 deg C. Avoid repeated freeze/thaw cycles. |
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Biohazard Information | This product contains sodium azide which is hazardous |
Usage Recommendations | WB: 1 ug/ml |
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Biological Significance | The SMC3 protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. |
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