Synonyms | Monoclonal PTP1B antibody, Anti-PTP1B antibody, PTPB 1 antibody, PTPB-1 antibody, PTP1B, PTPB-1, Protein Tyrosine Phosphatase Non-Receptor Type 1 antibody, PTPB 1, PTPN1 antibody |
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Cross Reactivity | Human |
Applications | WB |
Immunogen | PTP1B antibody was raised in Mouse using recombinant human protein purified from E.coli as the immunogen. |
Host | Mouse |
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Clone | 25B3 |
Isotype | IgG1 kappa |
Method of Purification | PTP1B antibody was purified by affinity chromatography. |
Form & Buffer | 0.15M Nacl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. With 0.03% sodium azide added as a preservative. |
Concentration | 1 mg/ml |
Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.. |
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Usage Recommendations | IP 1-2ul/400ul lysates |
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Biological Significance | PTPN1 is the founding member of the protein tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. |
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