Synonyms | Monoclonal Vimentin antibody, Anti-Vimentin antibody, Vimentin |
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Specificity | Reacts exclusively with vimentin, which is expressed in mesenchymal cells and mesenchymal derived tumors eg lymphoma, sarcoma and melanoma |
Cross Reactivity | Canine, Chicken, Goat, Hamster, Human, Monkey, Mouse, Rat, Swine, Zebrafish |
Applications | FC, IHC, IHC-F, IHC-P, WB |
Immunogen | Vimentin antibody was raised in Mouse using a cytoskeletal vimentin extract of calf lens as the immunogen. |
Host | Mouse |
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Clone | RV202 |
Isotype | IgG1 |
Form & Buffer | Supplied in PBS containing 0.09% sodium azide |
Usage Recommendations | FC: 1:100-1:200, IHC: 1:100-1:200, WB: 1:100-1:1000 |
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Biological Significance | Vimentin is used widely as a marker of the epithelial to mesenchymal transitions (EMTs) that take place during embryogenesis and metastasis, yet the functional implications of the expression of this type III intermediate filament (IF) protein are poorly understood. |
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