| Synonyms | p57Kip2antibody,p57antibody,Kip2antibody,Cyclin-dependentkinaseinhibitor1Cantibody,CDKN1Cantibody,p57/Kip2antibody |
|---|---|
| Specificity | Humanp57protein |
| Applications | IHC-P |
| Immunogen | p57/Kip2antibodywasraisedusingaprokaryoticrecombinantantigencorrespondingtoa116aminoacidregionoftheN-terminusofthep57protein. |
| Host | Mouse |
|---|---|
| Clone | 25B2 |
| Isotype | IgG1 |
| Form&Buffer | Lyophilizedfromliquidtissueculturesupernatantcontainingsodiumazide.Reconstitutein1mldistilledwater. |
| Storage | Storeat4degC.DONOTFREEZE.Returnto4degCimmediatelyafteruse. |
|---|
| UsageRecommendations | 1:50for30minutesat25degC.Therecommendedfixativeis10%neutral-bufferedformalinforparaffin-embeddedtissuesections. |
|---|
| ProductUse | p57antibodyisforuseinimmunohistochemistryonparaffinsections |
|---|---|
| BIOLOGicalSignificance | p57/Kip2isalsoknownasCyclin-dependentkinaseinhibitor1C(CDKN1C).p57/Kip2isatight-bindinginhibitorofseveralG1cyclin/Cdkcomplexesandanegativeregulatorofcellproliferation. |
| ImplicationsinDisease | MutationsoftheCDKN1Cgenewhichencodesp57,areimplicatedinsporADIccancersandBeckwith-Wiedemannsyndromesuggestingthatitisatumorsuppressorcandidate. |
Fitzgerald公司始于1989年,是全球著名的抗体、蛋白及其他科研试剂生产商。可提供超过45,000种产品,可为科研机构、诊断机构和制药公司提供包括单抗、多抗、天然和重组蛋白、ELISA试剂盒等多种试剂。
Fitzgerald的特色产品有PSA蛋白; CA 125, CA 15-3, CA 19-9 和 CA 50 抗体, GAPDH 抗体;Influenza单抗;心肌标志物如CKMM蛋白和Apo抗体;激素和类固醇多抗如**(testosterone)抗体, 孕酮(progesterone)抗体,和甲状腺素(thyroxine)抗体。



