Synonyms | Monoclonal TFPI antibody, Anti-TFPI antibody, TFPI antibody, Tissue Factor Pathway Inhibitor antibody, Anti TFPI antibody, Tissue Factor Pathway Inhibitor antibody |
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Specificity | Human |
Cross Reactivity | To be determined by end-user |
Applications | ELISA, FC, WB |
Host | Mouse |
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Clone | M105274 |
Isotype | IgG1 |
Form & Buffer | Liquid in 20mM TRIS, pH 8.0, with 150mM NaCl, and 0.1% NaN3. |
Concentration | 2.0 mg/ml |
Storage | Store at -20 deg C. Avoid repeated freeze/thaw cycles. |
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Usage Recommendations | Optimal conditions to be determined by end user |
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Biological Significance | Tissue factor pathway inhibitor (or TFPI) is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). While Xa is inhibited, the Xa-TFPI complex can subsequently also inhibit the FVIIa-tissue factor complex. TFPI contributes significantly to the inhibition of Xa in vivo, despite being present at concentrations of only 2.5 nM. |
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Fitzgerald公司始于1989年,是全球著名的抗体、蛋白及其他科研试剂生产商。可提供超过45,000种产品,可为科研机构、诊断机构和制药公司提供包括单抗、多抗、天然和重组蛋白、ELISA试剂盒等多种试剂。
Fitzgerald的特色产品有PSA蛋白; CA 125, CA 15-3, CA 19-9 和 CA 50 抗体, GAPDH 抗体;Influenza单抗;心肌标志物如CKMM蛋白和Apo抗体;激素和类固醇多抗如**(testosterone)抗体, 孕酮(progesterone)抗体,和甲状腺素(thyroxine)抗体。