Fitzgerald/CHCHD5 antibody/10R-3678/100 ul,Fitzgerald,,Fitzgerald,fitzgerald-fii,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Fitzgerald/CHCHD5 antibody/10R-3678/100 ul

产品编号：10R-3678-100ul

市场价：¥12240.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$612.00

品牌： Fitzgerald

公司：Fitzgerald,Inc.

公司分类：

商品介绍

OVERVIEW:

Synonyms	Monoclonal CHCHD5 antibody, Anti-CHCHD5 antibody, Coiled coil helix coiled coil helix domain containing 5 antibody, MGC11104 antibody, C2orf9 antibody, Chromosome 2 open reading frame 9 antibody, FLJ39671 antibody, CHCHD5, CHCHD 5, CHCHD-5, CHCHD 5 antibody, CHCHD-5 antibody
Cross Reactivity	Human
Applications	WB
Immunogen	CHCHD5 antibody was raised in mouse using a full length recombinant protein of human CHCHD5 (NP_115685) produced in E. coli as the immunogen.

SPECIFICATIONS:

Host	Mouse
Clone	6G8
Isotype	IgG1
Method of Purification	CHCHD5 antibody was purified by affinity chromatography.
Form & Buffer	Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	500 ug-1 mg/ml

STORAGE & SAFETY:

Storage	Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Usage Assay Information:

Usage Recommendations	WB: 1:2000

GENERAL INFORMATION:

Biological Significance	CHCHD5 contains 1 CHCH domain. Contains a myristylation motif followed by DUF domain and a CHCH domain. Over-expressed ChChd3 is localized only to mitochondria. Deletion of CHCH domain disrupts mitochondrial localization suggesting that CHCH domain is an essential targeting motif in ChChd3. In vitro protein import studies showed that in addition to cysteines in CHCH domain, myristoylation is also necessary for targeting the protein to the IM of mitochondria. Over-expressed ChChd3 in HEK 293 cells binds to PKA and shows a clear increase in phosphorylation at Thr10 upon stimulation with 8-CPT cAMP.

Biological Significance

CHCHD5 contains 1 CHCH domain. Contains a myristylation motif followed by DUF domain and a CHCH domain. Over-expressed ChChd3 is localized only to mitochondria. Deletion of CHCH domain disrupts mitochondrial localization suggesting that CHCH domain is an essential targeting motif in ChChd3. In vitro protein import studies showed that in addition to cysteines in CHCH domain, myristoylation is also necessary for targeting the protein to the IM of mitochondria. Over-expressed ChChd3 in HEK 293 cells binds to PKA and shows a clear increase in phosphorylation at Thr10 upon stimulation with 8-CPT cAMP.

品牌介绍

Fitzgerald公司始于1989年，是全球著名的抗体、蛋白及其他科研试剂生产商。可提供超过45,000种产品，可为科研机构、诊断机构和制药公司提供包括单抗、多抗、天然和重组蛋白、ELISA试剂盒等多种试剂。
Fitzgerald的特色产品有PSA蛋白； CA 125, CA 15-3, CA 19-9 和 CA 50 抗体, GAPDH 抗体；Influenza单抗；心肌标志物如CKMM蛋白和Apo抗体；激素和类固醇多抗如**(testosterone)抗体, 孕酮(progesterone)抗体,和甲状腺素(thyroxine)抗体。

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