Synonyms | Monoclonal ERN1 antibody, Anti-ERN1 antibody, Endoplasmic reticulum to nucleus signaling 1 antibody, ER to nucleus signalling 1 antibody, ER to nucleus signalling 1 antibody, Inositol-requiring protein 1 antibody, MGC163279 antibody, ERN1, ERN 1, ERN-1, ERN 1 antibody, ERN-1 antibody |
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Cross Reactivity | Human |
Applications | ELISA, FC, IF, IHC, WB |
Immunogen | ERN1 antibody was raised in Mouse using a purified recombinant fragment of human ERN1(aa282-433) expressed in E. coli as the immunogen. |
Host | Mouse |
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Clone | 9F2 |
Isotype | IgG1 |
Form & Buffer | Supplied as a liquid in ascitic fluid containing 0.03% sodium azide. |
Concentration | 1.0 mg/ml |
Storage | Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Recommendations | ELISA: 1:10,000, FC: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000 |
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Biological Significance | The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. |
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