| Synonyms | Monoclonal PDE4B antibody, Anti-PDE4B antibody, Phosphodiesterase 4B Camp-Specific antibody, Phosphodiesterase E4 Dunce Homolog Drosophila antibody, DKFZp686F2182 antibody, DPDE4 antibody, MGC126529 antibody, PDE4B5 antibody, PDEIVB antibody, PDE4B, PDEB 4, PDEB-4, PDEB 4 antibody, PDEB-4 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | FC, WB |
| Immunogen | PDE4B antibody was raised in mouse using a full length recombinant protein of human PDE4B (NP_002591) produced in HEK293T cells, as the immunogen. |
| Host | Mouse |
|---|---|
| Clone | 2B10 |
| Isotype | IgG1 |
| Method of Purification | PDE4B antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
| Usage Recommendations | FC: 1:100, WB: 1:2000 |
|---|
| Biological Significance | PDE4B is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. |
|---|
Fitzgerald公司始于1989年,是全球著名的抗体、蛋白及其他科研试剂生产商。可提供超过45,000种产品,可为科研机构、诊断机构和制药公司提供包括单抗、多抗、天然和重组蛋白、ELISA试剂盒等多种试剂。
Fitzgerald的特色产品有PSA蛋白; CA 125, CA 15-3, CA 19-9 和 CA 50 抗体, GAPDH 抗体;Influenza单抗;心肌标志物如CKMM蛋白和Apo抗体;激素和类固醇多抗如**(testosterone)抗体, 孕酮(progesterone)抗体,和甲状腺素(thyroxine)抗体。



