Fitzgerald/CDK7 antibody/10R-8530/100 ul,Fitzgerald,,Fitzgerald,fitzgerald-fii,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Fitzgerald/CDK7 antibody/10R-8530/100 ul

产品编号：10R-8530-100ul

市场价：¥5900.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$295.00

品牌： Fitzgerald

公司：Fitzgerald,Inc.

公司分类：

商品介绍

OVERVIEW:

Synonyms	MonoclonalCDK7antibody,Anti-CDK7antibody,CDK7antibody,cyclin-dependentkinase7antibody,39KDaproteinkinaseantibody,39proteinkinaseantibody,40kDaproteinkinaseantibody,BOS_19697antibody,C230069N13antibody,CAKantibody,CAK1antibody,CD7antibody,CDC2/CDK2antibody,4-activatingkinaseantibody,cdk-7antibody,Cdk7-PAantibody,CDK-activatingkinaseantibody,CDK-activatingkinase1antibody,cdkn7antibody,Celldivisionproteinkinase7antibody,CG3319-PAantibody,CR4proteinkinaseantibody,Crk4antibody,CRK4PK(CDC2-related-kinase-4proteinkinase)antibody,cyclindependentkinase7antibody,cyclin-dependentkinase7(homologofXenopusMO15cdk-activatingkinase)antibody,cyclin-dependentkinase7(MO15antibody,cdk-activatingkinase)antibody,cyclin-dependentkinase7(MO15homologXenopuslaeviscdk-activatingkinase)antibody,cyclin-dependentkinase7(MO15homologantibody,Xenopuslaevisantibody,cdk-activatingkinase)antibody,dCdk7antibody,DmCDK7antibody,Dmel_CG3319antibody,DmMo15antibody,HCAKantibody,homologofXenopusMO15Cdk-activatingkinaseantibody,kinasesubunitofCAKantibody,MO15antibody,p39mo15antibody,P39Mo15antibody,p40MO15antibody,p40[MO15]antibody,P40MO15antibody,proteinkinaseantibody,protein-tyrosinekinaseMPK-7antibody,serine/threoninekinasestk1antibody,serine/threonineproteinkinase1antibody,serine/threonine-proteinkinase1antibody,serine/threonineproteinkinaseMO15antibody,STK1antibody,TFIIHbasaltranscriptionfactorcomplexkinasesubunitantibody
CrossReactivity	Human
Applications	ELISA,IP,WB
Immunogen	CDK7antibodywasraisedinMouseusingarecombinanthumanproteinpurifiedfromE.coli(His/ABD-CDK7136-346a.a.)astheimmunogen

SPECIFICATIONS:

Host	Mouse
Clone	45H1
Isotype	IgG2bkappa
MethodofPurification	CDK7antibodywaspurifiedbyammoniumsulfateprecipitation
Form&Buffer	SuppliedinliquidforminHEPESbufferwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol

STORAGE&SAFETY:

Storage	Aliquotandstorefor1yearat-20degC,avoidfreeze/thawcycles

UsageAssayInformation:

UsageRecommendations	WB:1:2000-5000,IP:1ul

GENERALINFORMATION:

BIOLOGicalSignificance	CDK7formsatrimericcomplexwithcyclinHandMAT1,whichfunctionsasaCdk-activatingkinase(CAK),phosphorylatingcell-cycleCDKs.ItisalsoanessentialcomponentofthetranscriptionfactorTFIIH,whichphosphorylatestheC-terminaldomain(CTD)ofthelargestsubunitofPolII.Thisproteinisthoughttoserveasadirectlinkbetweentheregulationoftranscriptionandthecellcycle.Embryonicstemcells(ESCs)showsaveryunusualcellcyclestructure,characterizedbyashortG1phaseandahighproportionofcellsinS-phase.Thisisassociatedwithauniquemechanismofcellcycleregulationbytheactivityofcyclindependentproteinkinase(Cdk).

BIOLOGicalSignificance

CDK7formsatrimericcomplexwithcyclinHandMAT1,whichfunctionsasaCdk-activatingkinase(CAK),phosphorylatingcell-cycleCDKs.ItisalsoanessentialcomponentofthetranscriptionfactorTFIIH,whichphosphorylatestheC-terminaldomain(CTD)ofthelargestsubunitofPolII.Thisproteinisthoughttoserveasadirectlinkbetweentheregulationoftranscriptionandthecellcycle.Embryonicstemcells(ESCs)showsaveryunusualcellcyclestructure,characterizedbyashortG1phaseandahighproportionofcellsinS-phase.Thisisassociatedwithauniquemechanismofcellcycleregulationbytheactivityofcyclindependentproteinkinase(Cdk).

品牌介绍

Fitzgerald公司始于1989年，是全球著名的抗体、蛋白及其他科研试剂生产商。可提供超过45,000种产品，可为科研机构、诊断机构和制药公司提供包括单抗、多抗、天然和重组蛋白、ELISA试剂盒等多种试剂。
Fitzgerald的特色产品有PSA蛋白； CA 125, CA 15-3, CA 19-9 和 CA 50 抗体, GAPDH 抗体；Influenza单抗；心肌标志物如CKMM蛋白和Apo抗体；激素和类固醇多抗如**(testosterone)抗体, 孕酮(progesterone)抗体,和甲状腺素(thyroxine)抗体。

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